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Astellas
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Astellas
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Astellas
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Astellas
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Astellas
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LifeCycle Pharma A/S
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NanoBiomed Inc
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MyBiosource Biotechnology
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Becton Dickinson
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Image Search Results
Journal: Journal of Clinical Medicine
Article Title: Impact of Immunosuppressive Drugs on Fibroblasts: An In Vitro Study
doi: 10.3390/jcm11113107
Figure Lengend Snippet: Time-dependent influence of tacrolimus on mouse fibroblasts. ( A ) Total cell amount (baseline-corrected). Upregulation after 6 h at intermediate and high concentrations of 15 ng/mL and 20 ng/mL. Persistent increase in cell amount after 24 h using low and intermediate concentrations. No significant changes using high concentrations of 20 ng/mL after 24 h. ( B ) Average cell diameter was slightly reduced using TaC after 48 h for all concentrations. ( C ) Procollagen concentration with no significant changes using different concentrations of TaC. ( D ) Cell morphology evaluation using light microscopy between 6 h and 72 h. Overall increased cell confluence with longer inoculation periods. Columns and error bars represent the mean ± SEM (n = 12); significant ( p < 0.05).
Article Snippet: Cyclosporin (CsA; Sandimmun ® ),
Techniques: Concentration Assay, Light Microscopy